MICROBODIES IN EXPERIMENTALLY ALTERED CELLS
نویسندگان
چکیده
منابع مشابه
Microbodies in Experimentally Altered Cells
A rapid and sustained increase in the number of microbodies in liver and kidney cells can be induced in male rats by ethyl chlorophenoxyisobutyrate (CPIB), a hypolipidemic drug. This phenomenon permits investigation of several aspects of microbody behavior in experimental conditions. Reversal experiments demonstrate that liver cells revert to normal between 2 and 3 weeks after withdrawal of CPI...
متن کاملMICROBODIES IN EXPERIMENTALLY ALTERED CELLS VII. CPIB-induced Hepatic Microbody Proliferation in the Absence of Significant Catalase Synthesis
Previous studies (1-3) demonstrated a significant increase in number of microbodies (peroxisomes) and concomitant elevation in catalase activity in male rat liver following administration of ethyl-o, p-chlorophenoxyisobutyrate (clofibrate, CPIB), a hypolipidemic drug that lowers serum cholesterol and triglycerides in man (4) and in experimental animals (5, 6) . Neither the significance of micro...
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Masses of homogeneous electron-dense material accumulate in the cytoplasmic inclusions of cultured fibroblasts which have been infected with "wild" and "adapted" strains of human cytomegalovirus. The substance appears to be produced by microtubular membranes and the Golgi apparatus; ultrastructural histochemistry suggests that it is not lysosomal in nature nor is it comprised of lipids or polys...
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The cytoplasm of the hepatic cell contains, besides the well known organelles, microbodies, characterized by a single membrane, a finely granular matrix, and average dimensions below those of mitochondria. Microbodies, rare in normal cells, become more numerous in regenerative livers and in various pathological conditions. In these cases, they either evolve towards degenerative forms or else sh...
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PURPOSE To identify a casual pathway between the alteration in visual experience, due to form deprivation and hyperopic defocus, and the increase in eye growth, we searched for candidate genes having regulatory effects on eye growth under myopic conditions. METHODS The expression of the brain-derived neurotrophic factor, neurotrophin-3, sonic hedgehog, nerve growth factor, Six-3 and the Lh-2 ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1969
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.42.2.587